PRP Injection Plantar Fasciitis: Miracle Cure or Overhyped?

March

23

by Joe Armeli | Doctor of Physical Therapy

Learn how a PRP injection for plantar fasciitis may help resolve your pain.

In recent years, platelet-rich plasma (PRP) therapy has emerged as a potential treatment for plantar fasciitis, with studies yielding mixed results. We will dive into the process of PRP therapy, its efficacy in treating plantar fasciitis, and factors to consider when contemplating this treatment. As research continues to develop, PRP injections may become a more widely accepted and effective solution for those struggling with chronic plantar fasciitis.

Do PRP injections work for plantar fasciitis?

While still a newer treatment option studies have shown PRP injections for plantar fasciitis can help relieve pain.

Recent studies on platelet-rich plasma (PRP) therapy for plantar fasciitis have produced mixed results. Some research indicates that PRP injections can significantly reduce pain and improve function in patients with chronic plantar fasciitis, especially when other conservative treatments have failed. However, other studies have found little difference between PRP therapy and other treatments, such as corticosteroid injections or physical therapy.

It's important to realize PRP injections are a newer treatment option, and there is not a lot of research on them. This means there is no gold standard to follow and can lead to inconsistency in PRP preparation methods and injection techniques. Different practitioners may use diverse protocols, which can impact the effectiveness of the treatment. Factors such as the severity of the patient's condition, their overall health, and the duration of their symptoms can also influence treatment outcomes.

What is a PRP Injection:

PRP injections for plantar fasciitis work in bringing white blood cells to the plantar fascia to help it heal.

The PRP treatment process for plantar fasciitis is straightforward and minimally invasive. A medical professional will draw a small sample of the patient's blood, typically from the arm. The blood is then placed in a centrifuge to separate the platelet-rich plasma. Once the PRP is prepared, it is injected directly into the inflamed plantar fascia using ultrasound guidance to ensure accurate placement. The procedure usually takes less than an hour, with minimal downtime and discomfort.

How do PRP injections Work for Plantar Fasciitis?

Preliminary studies have shown success with PRP injections in helping treat plantar fasciitis.

Recent research suggests that plantar fasciitis may not primarily be an inflammatory condition but a result of scar tissue build-up from microtears in the plantar fascia. Scar tissue build-up occurs when there is insufficient blood supply and platelets in the affected area to promote healing. To counteract this, introducing platelet-rich plasma (PRP) therapy can help stimulate the healing process and alleviate the symptoms associated with plantar fasciitis.

PRP therapy involves extracting platelets from the patient's blood and injecting them back into the damaged area. These platelets are rich in growth factors that can help reduce inflammation, promote tissue regeneration, and ultimately accelerate healing. As a result, PRP therapy has gained traction as a promising treatment option for various musculoskeletal conditions, including plantar fasciitis.

What is the Success Rate of PRP with Plantar Fasciitis?

Three studies show a decrease in pain levels after a PRP injection for plantar fasciitis

Like we talked about there is not a whole lot of evidence out there right now on PRP, however I have compiled some of the results of studies I have found below. In general, it is a promising treatment. 

A study included 60 patients with plantar fasciitis who had not improved after conservative treatments for at least 3 months. The first group of 30 patients received an injection containing a corticosteroid. The second group of 30 patients received an injection of PRP. To assess the effectiveness of the treatments, patients were evaluated using a visual pain scale before the injection as well as 3 weeks and 6 months after the injection.

Six months after treatment, the average heel pain scores improved in both the steroid and PRP groups. The scores dropped from 6.2 to 3.4 in the steroid group and 7.33 to 3.93 in the PRP group. These improvements were significant when compared to their pain levels before treatment. However, there was no significant difference between the steroid and PRP groups in pain scores and overall improvement, measured at 3 weeks and 6 months after treatment.

Another study took people with plantar fasciitis who didn't improve after trying standard treatments for at least 1 year and were given PRP therapy. The injections were performed in a day clinic. Several scores measuring pain and function were collected before the treatment, as well as 3 and 6 months after the treatment.

Data was collected from 50 heels (44 patients). After 6 months, the average pain and function scores significantly improved. About 64% of patients were very satisfied and would choose to have the injection again. There were no reported complications.

PRP was effective for about 2 out of every 3 patients in these long-lasting cases. The treatment was safe, with no complications reported. The authors believe that PRP may have a role in treating plantar fasciitis and that further research, including a randomized trial, is warranted.

Our third study looked 25 patients with long standing plantar fasciitis and an average age of 44 years who were treated with PRP injections. Patient's pain levels were assessed before and after the injection, and the thickness of the plantar fascia was measured using ultrasound. The average follow-up time was 10.3 months.

Before the injection, the average pain level was 9.1 out of 10. Most patients had severe or moderate limitations in their activities. After the injection, the average pain level dropped to 1.6. Most patients (88%) were completely satisfied, while a few had reservations or were unsatisfied. After the treatment, most patients had no or minimal functional limitations. The ultrasound showed significant changes in the thickness and appearance of the plantar fascia after the PRP injection. No complications were reported.

Finally, in a study, 14 patients with chronic plantar fasciitis received three PRP injections and were evaluated 12 months after the procedure. The researchers used the visual analog pain scale for patients to report their pain.

After 12 months, most patients (64.3%) had excellent results, while others experienced good, acceptable, or poor outcomes. As measured by the VAS, pain levels significantly decreased from an average of 7.1 before treatment to 1.9 at the last follow-up.

Indications for a Platelet Rich Plasma Injection for Plantar Fasciitis

PRP injections can be an invaluable tool in the management of plantar fasciitis for the right candidates. The following are indications PRP injections may be right for you:

  1. Persistent pain despite conservative treatments: If you consistently follow a conservative treatment plan for your plantar fasciitis, such as stretching, strengthening exercises, and orthotics, but continue to experience pain, PRP may be a suitable option for you.
  2. Chronic cases: PRP injections can be particularly useful for patients with chronic plantar fasciitis, which has not responded to traditional treatments for an extended period, typically 6 months or more.
  3. A desire for non-surgical alternatives: PRP injections offer a minimally invasive option for patients who wish to avoid surgical intervention.
  4. Patients with physically demanding lifestyles: Athletes and those with jobs or hobbies that involve significant stress on their feet may benefit from PRP injections, as they can help speed up recovery and enhance healing.
  5. Recurring plantar fasciitis: If you have previously experienced plantar fasciitis and it has returned, PRP injections can effectively help treat your pain.

If you think you might be a candidate for PRP treatment, consult with a healthcare professional experienced in this therapy to discuss your options and determine the best course of action for your unique situation.

How Long Does PRP Take to Work for Plantar Fasciitis?

While some may get immediate relief after PRP injection for plantar fasciitis some may find relief after 6 months. This depends on multiple factors.

After receiving a PRP injection, being patient is essential as the injection promotes healing. The time it takes to feel relief depends on your plantar fasciitis severity, your overall health, and your rehabilitation protocol. Some people may start to feel better after 2 weeks, while others may take a few months.

A recent study examined pain levels before and after a PRP injection for plantar fasciitis at various time points: 2 weeks, 4 weeks, 3 months, and 6 months. The study found that pain relief began at 2 weeks and continued to improve, with the maximum relief reported at 6 months.

Is PRP better than steroids in plantar fasciitis?

PRP injection versus corticosteroid injections. PRP injections seem to be better.

Regarding injections for plantar fasciitis, PRP and corticosteroid injections are two popular options. But which one is more effective for pain relief and long-term healing?

As you know, platelet-rich plasma therapy utilizes your blood, which is enriched with growth factors, to promote natural healing and reduce inflammation. Steroid injections, conversely, involve injecting corticosteroids directly into the affected area to provide temporary pain relief and reduce inflammation.

One of the advantages of PRP over steroid injections is the more natural approach to healing. PRP stimulates the body's healing process by using the patient's blood, which could lead to long-lasting results. Steroid injections, while providing quick pain relief, may only offer temporary results and have potential side effects, such as tissue degeneration or weakening of tendons and ligaments.

Recent studies have shown mixed results when comparing PRP and steroids for plantar fasciitis treatment. Some studies have found PRP to be more effective than steroids in the long term, while others found no significant difference between the two treatments.

One study analyzed a total of 47 studies, including 2,989 participants and compared PRP injections to corticosteroid injections. 

In the short term, corticosteroid injections were more effective at reducing pain than blood injections. 

However, there were no significant findings for medium-term pain relief. 

In the long term, corticosteroid injections were less effective than platelet-rich plasma injections. 

Interestingly, corticosteroid injections had a similar effect on pain reduction as placebo injections in the short and medium term. 

It's important to note that your results may vary, and the best treatment option depends on the patient's specific needs and circumstances. Consulting with a medical professional, such as a physical therapist or orthopedic specialist, can help determine which treatment best suits your plantar fasciitis.

How many PRP Injections for Plantar Fasciitis?

The number of injections needed varies depending on the individual's unique condition, the severity of symptoms, and response to treatment.

When treating plantar fasciitis with PRP therapy, the number of injections needed varies depending on the individual's unique condition, the severity of symptoms, and response to treatment. However, some general guidelines should be considered when determining the appropriate number of PRP injections.

Based on the available research and clinical experience, many patients with plantar fasciitis find significant relief with just a single PRP injection. Studies have shown that a single injection can provide long-lasting relief for up to six months or longer.

That being said, some patients may require more than one PRP injection to achieve optimal results. In cases where the initial injection doesn't provide sufficient relief, your healthcare provider may recommend a follow-up injection. Working closely with your healthcare provider to monitor your progress and determine if additional injections are necessary is essential.

Can You Walk After a PRP Injection?

If you're considering PRP for plantar fasciitis, one of the most common questions is whether you can walk after receiving a PRP injection on your foot. The answer is yes, but with some important precautions.

Immediately following the PRP injection, your doctor will likely recommend avoiding putting too much weight on the treated foot for a short period, typically 24-48 hours. This allows the platelet-rich plasma to work on the affected area and reduces the risk of disrupting the healing process.

During the first few days after the injection, you may be advised to use crutches or a walking boot to help support your foot and limit weight-bearing. This minimizes discomfort and ensures that the PRP has the best chance of promoting healing effectively.

As the days go by, you can gradually increase the amount of weight you put on your foot and start to ease back into your daily activities. It's crucial, however, to listen to your body and not push yourself too hard, as overexertion could potentially slow down your recovery

Recovery After PRP Injection for Plantar Fasciitis Timeline

While recovery after a PRP injection varies quite a bit here is an example of a what your recovery may look like. 

Initial Support (1-3 weeks):

Some patients may need to wear a protective boot for 1-3 weeks to provide support and stability to the affected foot.

Phase 1 - Inflammation (3-5 days, up to 2 weeks): 

This phase focuses on localizing and eliminating damaged tissue to promote healing. During this time the PRP is an increasing blood flow, blood vessel permeability, and the migration of fluid proteins and white blood to the injured plantar fascia.

Phase 2 - Proliferation (1-4 weeks, up to 8 weeks): 

In this phase, the body releases cells that signal to synthesize collagen, which helps repair damaged tissue. It's important to remember during this time: soft tissue heals based on the type of stress it's subjected to. Complete rest is not recommended during this phase.

Phase 3 - Remodeling (1-3 months): 

The final stage of your rehabilitation focuses on remodeling, strengthening, and improving cellular organization within the healing tissue. During this time there is increased collagen organization and tissue and maturation.

Tips for a Successful Recovery 

To ensure the best possible outcome and a successful recovery, it is crucial to follow a well-designed rehabilitation program that strengthens and stretches key muscle groups. In this section, we will discuss the advantages of performing a rehab program tailored for plantar fasciitis, focusing on the foot, hip, and calf muscles, as well as stretching the calf muscles and plantar fascia.

Plantar fasciitis rehab program

My comprehensive ebook for plantar fasciitis will guide you through this exercise program, ensuring that you have all the necessary tools for a successful recovery.

Who are Platelet Rich Plasma Injections NOT for?

While PRP injections can effectively treat plantar fasciitis, it's important to recognize that not everyone is a suitable candidate for this procedure. Before considering PRP treatment, you must be aware of certain contraindications that may make this therapy unsuitable or unsafe for you. We'll discuss some common contraindications to PRP injections:

  1. Recent history of anticoagulant therapy: If you have recently undergone anticoagulant therapy or are currently on a course of blood-thinning medications, PRP injections may not be appropriate. These medications can increase the risk of bleeding or bruising during the procedure.
  2. Bleeding disorders: Individuals with bleeding disorders, such as hemophilia or Von Willebrand disease, are at an increased risk for complications during PRP injections.
  3. Pregnant or breastfeeding mothers: The safety of PRP injections during pregnancy and breastfeeding has not been well-established. As a precaution, it's generally advised that pregnant or breastfeeding women avoid PRP injections.
  4. Active malignancy, severe infection, or thrombocytopenia: PRP injections may not be suitable for individuals with an active malignancy (cancer), a severe infection, or thrombocytopenia (low platelet count). These conditions can compromise the safety and effectiveness of the treatment. 

Discuss your medical history with your healthcare provider before considering PRP injections.

Cost and Accessibility of PRP Treatment

PRP injections cost around $2,000-$500

While PRP therapy has many potential benefits, it's essential to consider its cost and accessibility. The price of PRP treatment can vary based on location and provider, typically ranging from $500 to $2,000 per session. As PRP is still considered an experimental treatment for plantar fasciitis, many insurance companies may not cover the cost. It's crucial to consult with your healthcare provider and insurance company to determine whether PRP therapy is feasible.

Conclusion

In conclusion, platelet-rich plasma (PRP) therapy has shown promise as a potential treatment for plantar fasciitis, particularly for patients who have not responded well to traditional conservative methods. While research is still in its early stages and results are mixed, PRP injections may offer a minimally invasive, natural approach to healing that could provide long-lasting relief for many patients. 

It is essential for individuals considering PRP therapy to consult with experienced healthcare professionals to determine if they are suitable candidates and to better understand the potential benefits, risks, and costs associated with this treatment.

 As further studies are conducted and more evidence is gathered, PRP therapy may become a more refined and widely accepted option in the management of plantar fasciitis.

About the author, Joe Armeli DPT

I'm Joe Armeli, a Doctor of Physical Therapy, Certified Athletic Trainer and Certified Strength and Conditioning Specialist, a movement enthusiast, and a fellow runner. I'm here to help you achieve your physical health and performance goals, whether you're just starting to run or are a seasoned vet. For questions or concerns, email me at joe.armeli.dpt@gmail.com. Look forward to hearing from you!

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